Khoma V. V.1, Martinyuk V. V.1, Mackiv T. R.1,2, Yunko K.1, Formanchuk R.1, Rarok Y. S.1,  Garasymiv O.1, Sahno A.1, Lushchak L.1, Kozachuk I.1, Gnatyshyna L. L.2, Stoliar O. B.1*

1 Ternopil Volodymyr Hnatiuk National Pedagogical University

2I.Ya. Horbachevsky Ternopil National Medical University

Glyphosate, the modified amino acid and organophosphonate compound, N-(phosphonomethyl)glycine, is the most sprayed and most used herbicide in the world [1]. Whereas it acts as the specific inhibitor of the enzyme 5-enolpyruvylshikimate-3-phosphate synthase, intrinsic for the plant and bacteria, blocking the synthesis of aromatic compounds in them, it was originally marketed as absolutely non-toxic for the animals [4]. However, during the experience of its application, the understanding of its by-side effects on the non-targeted organisms were elucidated. In particular, it causes the loss of the immune defense of the animals and human due to the impact on the symbiotic microorganisms [1, 4].